Mass spectrometry (MS) analysis measures the mass-to-charge ratio of ions to identify and quantify molecules in simple and complex mixtures. A mass spectrometer uses electric and magnetic fields to move and manipulate the ions. The types of molecules that can be detected, identified, and quantified include proteins, metabolites, drugs, lipids, and carbohydrates. MS is used in the fields of proteomics, clinical testing, drug discovery, and environmental and forensic testing.
Nuclear Magnetic Resonance (NMR) spectrometry is often used to investigate the properties of organic molecules and focuses on the magnetic properties of atomic nuclei. It is used to identify the structure of small organic molecules, determine protein and RNA structure, and study many types of dynamics.
Advanced analyses are readily conducted by experts within the cores. Contact them to find how they can help you with your research. You can also use Cores Search to look directly for an instrument or service by name or related term.
Services
- Consultation on small molecule and proteomics study design
- Data analysis and consulation
- Glycan analysis
- Mass cytometry
- Pharamacokinetics and pharmacodynamics
- Post translational modifications (PTMs)
- Protein and RNA determination
- Protein, RNA, small molecule interactions
- Protein/PTM quantification
- Sample preparation
- Tobacco exposure biomarkers
Mass Spectrometers
Proteomics:
Mission Bay -- UCSF Mass Spectrometry Facility
Parnassus -- Sandler-More Mass Spectrometry Core Facility
Small molecule/metabolomics:
Mission Bay -- Small Molecule Discovery Center
Zuckerberg GH -- Drug Research Unit, HDFCCC Tobacco Biomarkers Core
NMR Spectrometers
Protein, RNA, small molecules
Mission Bay -- UCSF Nuclear Magnetic Resonance Lab
Mass Cytometer (CyTOF)
Proteomics