By RRP on
January 31, 2012

The Spring 2012 RAP cycle introduces Core Exploratory Awards. Created by the UCSF Research Resource Program (RRP) in collaboration with CTSI-SOS, these awards enable researchers to explore the use of new technologies or services available in existing core facilities at UCSF.

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By RRP on
August 05, 2011

Quantitative imaging metrics to be linked to joint kinematics, kinetics, patient function and translated to the musculoskeletal clinic to improve patient management and outcome.

The National Institute of Arthritis and Musculoskeletal and Skin Disease (NIAMS) has recently funded a new Center of Research Translation, a joint collaboration between the UCSF Departments of Radiology and Biomedical Imaging, Orthopedic Surgery, Epidemiology and Biostatistics, and Physical Therapy and UC Davis. A total of 6.3 Million dollars (with 1.2 Million dollars allocated to UC Davis) will be used over the next 5 years to achieve the overall objective of the center, which is translation of quantitative imaging in osteoarthritis.

The Co-Principal Investigators are Sharmila Majumdar, PhD, UCSF Professor in Residence and Vice-Chair of Research in the Department of Radiology and Biomedical Imaging and Nancy E. Lane, MD, UC Davis Professor and Director of the Center For Healthy Aging.

The center’s combined team will include orthopedic surgeons, rheumatologists, imaging scientists, bioengineers, physical therapists, epidemiologists, and biologists. This team is built upon the strong foundation of interdisciplinary collaborations between these investigators, with a focus on translational research, and is supported by numerous individual investigator and programmatic grants that have established these collaborative research partnerships between these investigators and their respective institutions.

By RRP on
March 28, 2011

The Core Leadership Advisory Committee (CLAC) and CTSI have awarded the following grants to core directors and staff to attend training opportunities, based on the applications received earlier this year.

A total of $13,470 in funds have been awarded to core facilities at UCSF for 2011.

Awards for 2011 are as follows:

Clac Grants

By RRP on
March 21, 2011

UCSF has recently established a centrally managed ES Cell Targeting Core Facility. This facility will provide high-quality ES cell services to the UCSF Research community, and will replace the Transgenic Core Facility, which closed in August 2010. Services that will eventually be replaced include: ES cell culture, targeting using investigator provided constructs, clonal expansion and microinjection preparation. 

Dr. Chong Park will lead the development of this facility. Dr. Park is highly experience in this arena. Dr. Park has a number of years of experience in ES cell propagation, gene targeting and clonal expansion and is currently leading a miRNA knockout mouse project working with Michael McManus in the UCSF Diabetes Center. 

Potential long range plans for the facility include ES cell line derivation from knockouts, pronuclear, blastocyst, and lentivirus injections, as well as mouse phenotyping services.

Individual researchers who currently do their own ES cell targeting will not be impacted and can take advantage of the services provided by this core facility if they like. This facility will partner with the Gladstone Microinjection Facility to provide the full service mutant mouse production for UCSF and Gladstone researchers.

Development of this facility will continue with oversight from Advisory Committee members Michael McManus, Jeremy Reiter, Anthony Wynshaw-Boris and Averil Ma.